*, grey, silver, sword, dagger, blade, knife. Can be used to generate infinite batteries with the 48 hour energy pill. Upon hitting the floor, an obstacle, or an enemy, they burst into many smaller tears in all directions. Taking damage releases a ring of 10 high damage tears. Stats effected by this item are: Damage, Tears, Range, Speed. *astrology, astronomy, item room, treasure room, item room pool, nys, notyoursagittarius, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, bag, satchel, backpack, purse, satchel, brown. Unlocked by donating to the donation machine in the shop. The first and second familiars spawn after 15 hits, then 30 hits for the third and fourth. Turns pickups into their doubled versions while Isaac's numbers of coins, bombs, and keys are equal. e.g. This is essentially a superior version of The Common Cold item. When used, converts 2 soul or black hearts into 1 red heart container. Everytime you fire a tear, there is a chance that you will also fire three more tears in all cardinal directions. * library pool, library room, book room pool, angel room pool, god room pool, angel room item, With Dr. Fetus, this item will also cycle through random Bomb Modifiers (e.g. A familiar that follows Isaac and charges forwards very slowly, dealing 2.7 damage per tick to any enemies it comes into contact with. For the sake of simplicity for players, all damage values displayed are multiplied by 10 and rounded to the nearest number. The laser can apply status effects (e.g. The Holy Mantle might not seem like much during boss fights. All future pennies, keys, bombs and hearts will drop in pairs. Upon use, this item refreshes the current floor with brand new rooms, monsters and items, as if you had entered a new floor. Tears now have a random chance to apply a poison effect, causing double your tear damage per tick to enemies over time. When getting hit, this item has a chance to drop a soul heart or black heart. If playing as Cain or you have an item which modifies which eye you fire tears from, each shot has a 50% chance to do +2 Damage. * item room, treasure room, item room pool, red, horse shoe. Kills all enemies in the room, then kills Isaac three seconds later. ), Keeps the chance at 100% even after entering and leaving the angel room, meaning the door will not close after visiting, Makes it impossible to find Devil Rooms again, unless you find a way to remove or reroll this item away, or find the Duality item. Effect persists between rooms while the time period is active, Speed Down - Reduces your speed stat by -0.12, Speed Up - Increases your speed stat by +0.15, Tears Down - Reduces your tears stat by -0.28, Tears Up - Increases your tears stat by 0.35, Telepills - Teleports you to a random room when used. No longer triggers if there are fewer than 2 enemies in the room. At the stats screen, pressing Alt + F2 will sync unlocks with Steam achievements. Gives a chance to heal 1/2 a red heart every time the in-game timer hits a new minute. The crown will glow blue while active, if inactive it will appear grey. Based loosely on the Steam Workshop mod created by Extreme Ninja Home Makeover with changes by Edmund McMillen, *, lepracy, leprasy, leprosy, pink, red, bloody, lump. Using. * key master pool, key beggar pool, key judgement pool, shop room pool, shop item pool, red, heart, Unlocked from Challenge #24 - PAY TO PLAY, Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect), Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. Rings have infinite range and travel until they hit a wall. Contact damage is also dealt to enemies equal to the amount of coins Isaac is currently holding. Upon use, consumes a coin and deals damage to everything in the room. When you pick this item up, the Mysterious Paper trinket is spawned on the ground. The multiplier will no longer be lost when hitting poops or TNT barrels. A familiar blue head that will follow Isaac and fire tears copying his tear damage. Hitting Mom's Dressing Table with an explosive will cause it to vanish and drop 1-4 pills. Each time an item is generated by the D4, it is also removed from the pool. The damage dealt by the Boomerang is equal to double your tear damage. If you're a gamer that strives to see all aspects of the game, you are likely to spend around 279 Hours to obtain 100% completion. Isaac starts with this item after it is unlocked. THEGHOST. Afterbirth added 63 new secrets, for a total of 339. Upon use, spawns a random item from the current room's item pool, with a chance to spawn. Teleports the player to the first room of the current floor. Gives Isaac a random tarot card when picked up. FRA1DN0T. Gives Isaac a guaranteed devil or angel room on every floor that they can appear, even if you have already beaten the boss and it didn't show up originally. Has a chance to drop from the Sloth miniboss fight. The Tonsil familiar counts as a passive item but does not appear in any item pools, meaning this trinket is the only way to find it (aside from starting with it as Eden) and make it appear in your Items Collection page. Using the box again will put the picked up items back on the floor again, allowing you to move things between rooms, Can move any of the following: Batteries, Items, Trinkets, Hearts, Keys, Bombs, Coins, Chests and more. For example, an item which usually gives +1 Damage would instead give a small 'all stats up'. Rainbow Baby's tears can choose from any of the other familiars, such as homing, spectral, tar shots etc. * secret room pool, item room, treasure room, item room pool, white, lump, oval. * item room, treasure room, item room pool, gold, ingot, bar, orange. Using the portable slot takes a coin and has a chance to give a pickup - similar to how the normal slot machines work. * item room, treasure room, item room pool, the lost item pool, starting, red, blood, drop. UNLOCK: Unlock this card by beating Challenge #7 (Suicide King). Doubles the yield of hearts, coins, bombs and keys that spawn from non-red chests. If a tear blocks something, both Isaac's and the enemies tears are destroyed. A familiar angel which follows Isaac and fires Sacred Heart tears which deal 10 damage at -25% shot speed and a reduced fire rate. Killing a Devil Beggar, Key Master, or Shell Game Beggar gives you an increased chance of finding Angel rooms instead of Devil rooms. Stomp damage (i.e. In Afterbirth this item has a 20% chance to cause enemies to drop black hearts if it was poisoned. UNLOCK: Unlock this item by defeating Lil Horn 20 times. If held when you touch the chest after the Satan or Isaac fight and you don't have the relevant item to go to the next floor (Polaroid or Negative), you have a small chance to be taken there anyway. * item room, treasure room, item room pool, red, white. When used in a room with 2 items you can choose from (e.g. * anti gravity, item room, treasure room, item room pool, anti gravity, atom, nucleus. Can be picked up as soon as they hit the ground. lightning, bolt, hot garbage. Allows Mom's Wig to spawn a maximum of 10 spiders at once instead of 5. Can be dropped when exploding mushrooms in the environment that are usually found in the Caves/Catacombs and in secret rooms. 5 Dot - Reroll and restart the current floor (Forget Me Now effect). If your speed stat is already higher then that value is still used. In the burst of tears is a kidney stone which deals a lot of damage. Makes Isaac very small like a baby, reducing his hitbox size. In the Womb and beyond this deals 1 full heart of damage. +0.2 Damage Up for each 'evil' item you have. Item Pool: Item Room, Secret Room, Super Greed Miniboss, * secret room pool, item room, treasure room, item room pool, 25, grey, gray, silver. item when picked up again. * item room, treasure room, item room poolgrey, gray. Abel's tears do the same as Isaac's base damage (3.5). A second Pentagram will give an extra +5% chance. Missing Poster: Dying in a sacrifice room while holding this trinket will reveal a puzzle piece on the death screen. * item room, treasure room, item room pool, robo baby, robot baby, white, grey, gray, silver, red. Gives you a different tear effect with every tear that you fire. Does not appear to affect your damage and only the hitbox size of tears. Reveals the entrance to secret rooms and automatically opens the hole, removing the need for bombs to enter. *, white, grey, gray, pill, medicine, drug. * item room, treasure room, item room pool, dice pip, starting, pink, red, cube. A baby that resembles Miroslav from LeatherIceCream's "Poor 4" animations. * astrology, astronomy, item room, treasure room, item room pool, h, blue, glow, Tears Down by exactly half (Tear delay * 2). UNLOCK: Unlock this item by beating Greed Mode with Samson. If the obstacle it is attached to is destroyed then it will continue rolling in the direction it was previously travelling until it meets another wall or obstacle. UNLOCK: Unlock this item by beating Lokii for the first time. * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, shop item pool, pink, red, Item Pool: Boss Room, Challenge Room, Beggar, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, brown, bowl, grey, gray, poop, fly, Item Pool: Boss Room, Beggar, Challenge Room, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, can, tin, brown, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, dog, brown, sack, bag, fly, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow, * boss room pool, boss room item, brown, leather, bag, sack. If a tear misses an enemy, there is a chance for the multiplier to be reset back to 1. Once picked up, the gold heart will drop money on the floor the next time Isaac loses a heart. Once picked up, you gain unlimited bomb use for the rest of the floor. Luck has no effect on the rate at which Tech.5 fires and does not scale with items that increase your tears stat. UNLOCK: Unlock this item by beating Delirium on The Void floor with ???. Lowers your spacebar item charge rate by 1. Roughly 25% of the time, Isaac shoots an extra tear, like 20/20. A toothy baby with a slice of toast for a head that resembles Breadmeat, a member of the Isaac community. Monster replacements will now only occur with enemies spawned as part of the room layout. * golden chest pool, gold chest pool, item room, treasure room, item room pool, follower, everyone knows it's abel, brown, grey, gray, dead, head, grey, green. rocks). UNLOCK: Unlock this item by getting a 3 win streak. Spawns a friendly Mulligan that walks around the room. An adorable friendly blue spider that walks around the room laying other blue spiders which attack enemies. All of Isaac's bombs now having a homing effect when placed on the floor. For the current room, tears now have the Spoon Bender effect, which allows them to curve towards enemies and gives them a purle appearance. *, red, white, stripe, hat, clown, waldo, wally, Causes random enemies to 'lag' at random intervals, causing them to freeze in place for a second, The lag effect can also apply to tears, projectiles and consumables on the ground, While held, this trinket has a 25% chance to double up any end of room drops (similar to the Contract from Below effect), Isaac's Luck stat affects how often the lag effect occurs, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Freezenification, UNLOCK: Complete 7 Daily Challenges (30 on console), A one-time use item that spawns a random item from the current room's item pool, with a chance for it to spawn Lump of Coal or The Poop instead, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Mills, *, green, red, present, bow, xmas, christmas. 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