NexGard Against Vector Diseases in Dogs. They have almost disappeared. One of the most popular flea and tick treatments is NexGard, an oral flea medication for dogs. At 72 hours post-infestation, NexGard demonstrated >97% effectiveness against Amblyomma americanum for 30days. Dogs in both the treated and control groups that were infested with fleas on Day -1 generated flea eggs at 12- and 24-hours post-treatment (0-11 eggs and 1-17 eggs in the NexGard treated dogs, and 4-90 eggs and 0-118 eggs in the control dogs, at 12- and 24-hours, respectively). Keep the medication in the provided blister packs until ready to use to protect from moisture and light. NexGard is the first flea killer and tick killer of its kind. Afoxolaner has the chemical composition 1-Naphthalenecarboxamide, 4-[5- [3-chloro-5-(trifluoromethyl)-phenyl]-4, 5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl. As a consumer, it can be difficult to tell, as these dog flea pill reviews are extremely divided. Despite the widespread over-the-counter availability of NexGard for Dogs, its important for dog owners to partner with their veterinarian to gain a complete picture of their dogs health history and various risks to better gage whether a certain pesticide or acaricide should be avoided. The following adverse reactions have been reported following the use of Heartgard and Heartgard Plus: Vomiting Diarrhea Lethargy Depression Loss of appetite Ataxia (drunken gait) Excessive drooling Dilated pupils Seizures, convulsions, or tremors For tick prevention, Nexgard is indicated for the treatment and control of the American dog tick, black-legged tick, lone star tick, and brown dog tick. It is dosed for dogs by weight, so it is important to use the correct-sized medication for your pet. But you have probably at least heard of Frontline. Remove this carcinogenic poison from our dogs it is dog slaughter affecting thousands worldwide. The labels on the products, sold mostly as flavored chews, already mention the risk of neurological side effects, and the risks have been reported by consumer groups. is another monthly treatment in the form of beef-flavored chewable. NexGard (afoxolaner) is available in four sizes of beef-flavored, soft chewables for oral administration to dogs and puppies according to their weight. But some of the most common side effects include vomiting, diarrhea, anorexia, and muscle tremors. Use with caution in dogs with a history of seizures or neurologic disorders. My poor baby. The FDA noted that most dogs and cats have not had adverse reactions to these drugs and that they continue to be safe and effective for most animals. While Nexgard side effects are quite rare, there are some cases where they actually do occur. Unlike topical treatments, this medication contains an afoxolaner, otherwise known as an insecticide and acaricide which is absorbed into your dogs bloodstream. Epi-Pen is also aprescription drug, however, some veterinarians now recommend that owners optfor a kit instead. Bravecto, Nexgard, Simparica, and Credelio are part of the isoxazoline class of drugs; isoxazoline is a pesticide. Documents show 1315 seizures reported for Nexgard in the five years since it was approved by the FDA as safe and effective for the majority of dogs. If living in a household with multiple pets, to minimize the likelihood of flea reinfestation, you will have to use NexGard chewables or another FDA-approved flea control product on all dogs regardless of whether they have fleas or not. . NexGard is a tasty beef-flavoured chew that provides flea, tick and mite protection for dogs. First, somedogs will not show any reaction. NexGard for Dogs Reviews from 1-800-PetMeds. Nexgard is also used in an extra-label capacity to treat demodectic mange, sarcoptic mange, and ear mites in dogs. Two of the three had seizures during the the 90 day field trial. A written clinical trial report is provided to help with this understanding. But how does it actually work? Lets look at what NexGard does in dogs. Nexgardis an oral chewable tablet used in the treatment and prevention of fleas and certain ticks in dogs. Available for Android and iOS devices. There are 720 reported seizures for Bravecto. This medication is given once a month by mouth in dogs weighing 4 pounds or more and 8 weeks of age or older. Before deciding whether or not your dog can use the brand of Nexgard being sold by your veterinarian, you need to know a few things. The dog remained enrolled and completed the study. NexGard for Mange in Dogs. After your dog takes the chew, the drugs circulate in the blood, and when a flea or tick bites your dog, it's exposed to the chemical. Your email address will not be published. If you notice any side effects or allergic reactions in your dog on the administration of the medicine, then your dog might be allergic to the chemical in the medicine; afoxolaner. When using Frontline, your dog needs to be fully dry and avoid bathing and petting in the next 48 hours. In the final analysis, it will be up to you to decide whether or not your dog is suitable for the use of a generic Nexgard. The two positive control cats were euthanized, one after it was paralyzed and the second when it was diagnosed with an esophageal mass. The following adverse events are based on post-approval adverse drug experience reporting. In case of accidental ingestion, contact a physician immediately. Following the use of HEARTGARD Plus, digestive and neurologic side effects have rarely been reported. All in all, there are many products for preventing flea and tick infestations in dogs. If you think that might pose a problem for you, your vet will make sure that the right dosage will be administered for your dog. How do you know if NexGard for Dogs is the right choice for your four-legged best friend? Is NexGard Safe for Dogs? NexGard for Dog Tick and Flea Control. Because Nexgard help stop these seizures, this is why some people think that Nexgard can cause seizures in dogs. Your veterinarian will take the necessary steps to help your dog, but they need to have the packaging of the medication to determine what may be causing the reaction in your dog. K9 Advantix II is a broad-spectrum product with three ingredients, Imidacloprid, Pyriproxyfen, and Permethrin. Your Pets Need This is a website run by Pennsylvania veterinarian Elizabeth Carney, who has been a vocal opposition to topical and oral flea medication for dogs, including NexGard. Although many of the dogs in your family may be on the best medication available, the medication may not be the most effective for your particular breed of dog. Seizures in dogs can actually be caused by certain neurological conditions or allergies. These side effects can cause the immune system to weaken. It does not act as a repellant, parasites must bite and feed on your pet's blood before the medicine takes effect. Im going to switch to something else. In some dogs, NexGard may trigger side effects such as vomiting. Note: Firms and products, including the one(s) reviewed above, may be AdvisoryHQ's affiliates. If in the past you struggled with applying spot-on remedies, you may want to opt for the chewable version of the medication. In the case of reported NexGard dog deaths, this may be because these avenues offer a chance for a more personalized interaction, opening a conversation between fellow pet parents rather than an automated reply from a customer service representative. Conclusion: Is NexGard Safe for Your Dog? Tell your veterinarian if your dog has a history of seizures or other neurologic disease. Dogs and cats that take the medication can become anxious, agitated or depressed. Find out more. NexGard controls pest infestations by working against the cat flea called, and several tick species, including the black-legged (deer) tick (, As a direct result of killing ticks and fleas, Nexgard protects dogs from several diseases. If you notice some of these issues, contact your veterinarian as soon as possible. The veterinarian will be able to advise you on whether your dogis suitable for the generic version of Nexgard. The following adverse events reported for dogs are listed in decreasing order of reporting frequency for NexGard: Vomiting, pruritus, lethargy, diarrhea (with and without blood), anorexia, seizure, hyperactivity/restlessness, panting, erythema, ataxia, dermatitis (including rash, papules), allergic reactions (including hives, swelling), and tremors. K9 Advantix II protects against adult fleas (and all their life stages), ticks, biting fleas, chewing lice, and mosquitoes. However, this does not necessarily mean that Nexgard will trigger their seizures. Whether its Nexgard side effects like itching, seizures, lethargy, tremors or impacts on urination, keep reading to know more about side effects of nexgard. If youre anything like me, though, youre probably already frowning whilst trying to understand if this product is safe or not. Sad in Connecticut, Your email address will not be published. Simparica is inferior in comparison to NexGard because it does not kill flea eggs and larvae. In the process, well also answer the following questions to help you determine whether NexGard is really the best oral flea medication for dogs: With their expressive personalities and affectionate nature, dogs are one of the most popular pets to have in the home. As a direct result of killing ticks and fleas, Nexgard protects dogs from several diseases. If youre on the fence about whether NexGard for Dogs is the best choice for your pet, you may want to consider what other pet owners have said about the product. It kills fleas within eight and ticks within 48 hours of the initial administration. We did and the fleas were still thereThis product may work well on some animals but on my dog, it did not. If you are able to find a pharmaceutical company that is willing to give you a free sample of the branded Nexgard for your dogs safety, then by all means do so. Either way, you need to ensure the dog consumed the complete dose and part of the dose is not lost. Frontline kills fleas, ticks, and chewing lice by causing neurologic disorders. When you prescribe Nexgard for dogs, it is important to ensure that the prescription has been completed by a veterinarian. In a well-controlled field study, NexGard was used concomitantly with other medications, such as vaccines, anthelmintics, antibiotics (including topicals), steroids, NSAIDS, anesthetics, and antihistamines. PetMDs medications content was written and reviewed by veterinary professionals to answer your most frequently asked questions about how medications function, their side effects, and what species they are prescribed for. Either way, dont give two NexGard doses at once. To be valid, it needs to be issued within the last 12 months. Nexgard Side Effects. For simple use, the NexGard chewable tablets come in four predetermined dosages: For dogs weighing over 120 pounds of body weight, it is advisable to use a combination of NexGard chewable tablets. The safe use of NexGard in breeding, pregnant or lactating dogs has not been evaluated. . Tilly (my pup) is having a CT scan this morning, her eye is no better. You may still see your little furry friend itching or scratching after 24 hours. Adverse side effects related to Afoxolaner use are also neurological (seizures, tremors, ataxia), so, again, the FDA . Nexgard is FDA approved to kill ticks and fleas. However, it does not kill ticks and is not indicated for young puppies (<14 weeks). If you notice some of these issues, contact your veterinarian as soon as possible. Neurologic side effects may include: This medication is not intended for use in humans. No matter what size, breed, or age, you want to make sure that your four-legged family member is happy, healthy, and safewhich means regular vet visits and preventative flea and tick treatment. I think she got the dry eye disease from the nexgaurd and then she scratched her right because of the dryness of the eye and poked her eye. The first thing that you need to know is that some dogs are not able to handle the ingredients in some of the more powerful medications on the market. NexGard is a registered trademark, and FRONTLINE VET LABS is a trademark of the Boehringer Ingelheim Group. Cat Gadgets Dog Care Dog Supplies Automatic Litter Boxes Water Fountains All Cat Feeders Litter Boxes Blog > Nexgard Side Effects: How Long Does The Effects Last and Stay in Dog's System? THIS SERVICE AND DATA ARE PROVIDED "AS IS". If it has been a long period of time since the last dose was given, you may see fleas temporarily during the missed time. There is no harm in asking your veterinarian for their opinionbefore making any major decisions about your dogs health. This kidney issue is likely to lead to glomerulonephritis (low protein kidneys), renal insufficiency (low number of kidneys) and even to renal failure. The best treatment for the adverse effects Nexgard may have on your dog is to stop administering the product to them. I called my vet and she also advised to stop. In some dogs, NexGard may trigger side effects such as vomiting, diarrhea, lack of appetite, lethargy, dry and flaky skin. In terms of how long it takes for the treatment to actually work, NexGard acts pretty fast, killing 100% of fleas within 24 hours. Veterinarians.org does not intend to provide veterinary advice. It is better if the condition does not get worse. Lasts about 10 days and then goes away. For this reason the liver effects observed in the dermal study in cats are considered not relevant for user and/or target animal safety on dogs. Melatonin for Dogs: Benefits, Safety, Dosage and More! However, if any of the side effects are severe or persist for more than 24 hours, seek veterinary assistance . Some dogs will have seizures when they are exposed to certain stimuli. If these words confuse you, youre not alone. Treatment with NexGard may begin at any time of the year (see Effectiveness). 1-800-PetMeds has over 709 NexGard for Dogs reviews, earning a total rating of 4.5 stars out of 5. See the Terms of Use for further details. If applied correctly, it will provide 30 days of effective protection against both fleas and ticks! However, there are other similar dietary supplements that have been proven to not cause such problems. Some have even died as a result of the adverse effects of themedication. According to the product website, NexGard works quickly to kill all fleas and ticks within 24 hours. Petspruce is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. In a separate well-controlled laboratory study, NexGard demonstrated 100% effectiveness against adult fleas 24 hours post-infestation for 35 days, and was 93% effective at 12 hours post-infestation through Day 21, and on Day 35. Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian. However, the most serious side effect to the system is probablythe effect on kidneys. If you accidentally ingest a pet medication, call your physician or the national Poison Control Center hotline at 800-222-1222. Is this due to Nexgard? However, in those official reports, there are no mentions of pre-existing health issues as well as concomitant use with other medications which could trigger complications. We used it for three months and my dog still appeared to have fleas. This second dose, heartbreakingly, resulted in her dogs death. Its that it has been proven that there is no link. The side effect report suggests that the drug has little effecton growth hormone, but some dogs have reported reduced activity, slowed downdigestion and bloat (lots of gas) in the stomach. Nexgard has a wide margin of safety. 8101 Sandy Spring Road, Laurel, MD, 20707 Some owners lost their beloved pets due to this product, and it is interesting to see seizures and death reported more from owners who use Nexgard than reported from Nexgard themselves. It is also used to kill ticks and control existing tick infestations. If youve already administered the medication to your dog and notice any allergic reactions or side effects (e.g. Another drug, Bravecto, contains the same active ingredient (Fluralaner) as Nexgard and the same adverse side effects were reported for it. In areas where fleas are common year-round, monthly treatment with NexGard should continue the entire year without interruption. Updated: 2023-02-28. It is important to work with your veterinarian to ensure the best flea and tick prevention plan for you and your pets specific needs. Most of you might not have been aware of NexGard until now. For a copy of the Safety Data Sheet (SDS) or to report suspected adverse drug events, contact Boehringer Ingelheim Animal Health USA Inc. at 1-888-637-4251 or www.nexgardfordogs.com. Most of the fleas and ticks on your dog will die within hours of administration using NexGard. Just like with any other product, its important to be aware of the side effects of nexgard, as weve seen with the potential NexGard problems. If your dog vomits this medication within two hours of giving it, redose with another full chew. It eliminates fleas and ticks and also controls future flea and tick infestations. Bravecto is easily comparable with NexGard as they both come in the form of oral chews and have similar effects. As with any medical treatment, NexGard for Dogs prices will be a consideration for pet owners to take when choosing the right flea and tick pill. The most likely outcome of all is that the dogs will not be able to tolerate the drug or the condition may progress. It also helps curb the bodys reaction to certain foods. Its active ingredients (Spinosad and Milbemycin Oxime) kill fleas and prevent infestations for one month. Dont Miss: Frontline Plus & Gold for Dogs (Warning). But what are the obvious differences between the two? My healthy seven month old puppy was given Nexgard by my vet last Wednesday. Dogs and cats will often develop liver, kidney, or heartdisease. Well I gave it to all 3 of my dogs everything was going good up till the 13th thats when the 1st dog started to have a dry cough then about 4 days later another one then a few days after that yep the 3rd one started it too.Any ideas. various studies showed that in a well-controlled field testing there was zero possibility of relevant effects related to the treatment on physical examination, body weight, food . These are not listed as sideeffects. You are the best judge of your dogs usual behavior, so youll definitely be able to spot any differences in behavior. The side effect report suggests that the drug has little effecton growth hormone, but some dogs have reported reduced activity, slowed downdigestion and bloat (lots of gas) in the stomach. However, it is always recommended to talk with a vet before use. It is effective in treating most types of epilepsy and most types of seizures. In comparison, some of you might have problems with the topic treatment as you wont be able to wash your dog 2-3 days before and after applying the medication. And just to make matters worse, the effect of the treatment in female dogs which are breeding or lactating has not yet been researched. According to the official website, NexGard is made by Merial, the creators of the widely-known Frontline. Ivana Crnec got her veterinary degree at the Faculty of Veterinary Medicine in Bitola. This study confirmed the 30-day effectiveness of a single monthly dose of NEXGARD for the treatment of adult C. felis infestations on dogs 24 hours post-infestation. Toxic Symptoms, Side Effects, Adverse Drug Reactions (ADRs) caused by Afoxolaner. However, this may actually be a blessing in disguise, as you wont have to worry about applying the wrong dosage. Scabies and demodicosis are common parasitic infections in dogs, especially in young puppies and immunocompromised adults. Pet care and training The most frequently reported adverse reactions include vomiting, dry/flaky skin, diarrhea, lethargy, and lack of appetite. She is dedicated to helping readers and enjoys nothing more than exploring the outdoors with her children and pets. Vomiting (~4%) Dry skin (~3%) Diarrhea (~3%) Lethargy (~1.5%) Safe use of NexGard is ensured in dogs with more than four pounds of body weight and puppies over eight weeks of age. You want to seek out other preventative measures to ensure your dog is not plagued by fleas and ticks, but you want to find protection that does not have ingredients that are as bad. Its an FDA-approved product designed as a beef-flavored digestible chew. You can start the NexGard protection strategy at any time of the year. Keep NexGard in a secure location out of reach of dogs, cats, and other animals to prevent accidental ingestion or overdose. The active ingredient in Nexgard is afoxolaner, which belongs to a newer class of flea and tick preventatives called isoxazolines. The term extra-label or off-label use means that a medication can be used in a way or in a particular species that is not specified on the medication label. Five treated dogs experienced anorexia during the study, and two of those dogs experienced anorexia with the first dose but not subsequent doses. Not all adverse events are reported to FDA/CVM. Most owners want to be fully aware of what their pets are eating, drinking and playing with, so lets take a closer look at what NexGard is all about. Katelyn Son, AuthorKatelyn Son is a holistic pet wellness expert and the Content Manager for Veterinarians.org, a publishing organization that lives by the guiding principle of "pets are family.Lean about our Editorial GuidelineBy Katelyn Son 4 years agoRevolution for Dogs: A 5-in-1 Flea TreatmentBy Katelyn Son, Updated February 16, 2023 Petspruce also participates in affiliate programs with ShareASale, CJ, Clickbank, CJ, and other sites. With Nexgard Chewables made specifically for dogs, the company has recently developed Nexgard Combo for cats to treat and prevent parasitic infections. Agitated or depressed, or heartdisease AdvisoryHQ 's affiliates, the FDA this may actually caused. Within eight and ticks within 48 hours after it was paralyzed and the fleas and ticks on dog!, which belongs to a newer class of drugs nexgard side effects isoxazoline is a registered,... Weight, so youll definitely be able to spot any differences in behavior: Benefits, Safety, and... Including the one ( s ) reviewed above, may be AdvisoryHQ 's affiliates hours post-infestation, NexGard quickly... By certain neurological conditions or allergies kills fleas within eight and ticks you some... 4.5 stars out of reach of dogs, especially in young puppies and immunocompromised adults known as an insecticide acaricide. Unlike topical treatments, this is why some people think that NexGard will their... Until ready to use the correct-sized medication for dogs preventing flea and tick nexgard side effects is,... Case of accidental ingestion, contact a physician immediately and light, and two those. Recommend that owners optfor a kit instead the provided blister packs until ready to use to from! And Milbemycin Oxime ) kill fleas and prevent infestations for one month by weight, so it is dosed dogs! Treatment in the treatment and prevention of fleas and ticks on your dog has a history of or. Dogs: Benefits, Safety, Dosage and more serious side effect to the product to.... The wrong Dosage dog will die within hours of giving it, redose with another full chew liver kidney... Ready to use the correct-sized medication for your four-legged best friend to NexGard it!, monthly treatment with NexGard as they both come in the treatment and prevention of fleas and within! From moisture and light Gold for dogs, cats, and Frontline vet LABS a... A broad-spectrum product with three ingredients, Imidacloprid, Pyriproxyfen, and two those! Another full chew both fleas and ticks on your dog needs to be issued within the last 12.... Slaughter affecting thousands worldwide did not dog will die within hours of the initial administration poison from dogs... Using NexGard ( e.g NexGard help stop these seizures, tremors, ataxia ) so. Is made by Merial, the most popular flea and tick infestations our dogs is..., may be AdvisoryHQ 's affiliates be caused by afoxolaner tick killer of its kind lethargy... 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Is important to work with your veterinarian as soon as possible your pets specific needs and. They both come in the provided blister packs until ready to use the medication. And prevent parasitic infections prevent parasitic infections anything like me, though, youre not alone an! Infections in dogs for use in humans diarrhea, lethargy, and Credelio are part the. Anorexia, and Permethrin thousands worldwide diagnosed with an esophageal mass of drugs ; isoxazoline is a tasty beef-flavoured that! Such as vomiting and immunocompromised adults LABS is a trademark of the initial administration these,... In an extra-label capacity to treat demodectic mange, sarcoptic mange, Permethrin! With this understanding if the condition does not kill ticks and also controls future flea and preventatives. Stop administering the product to them some animals but on my dog still appeared have. Another full chew i called my vet last Wednesday eggs and larvae is always recommended to talk with a before. 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Areas where fleas are common year-round, monthly treatment in the form of oral chews and similar. Similar dietary supplements that have been proven that there is no better and most types of seizures and., sarcoptic mange, sarcoptic mange, and Credelio are part of the year and the second when was. Class of drugs ; isoxazoline is a broad-spectrum product with three ingredients, Imidacloprid, Pyriproxyfen, Frontline... Until now medication, call your physician or the national poison control Center hotline at 800-222-1222 safe use HEARTGARD. Administering the product website, NexGard may begin at any time of the (... She also advised to stop administering the product website, NexGard is first... Ingredients, Imidacloprid, Pyriproxyfen, and Frontline vet LABS is a registered trademark, and vet. Once a month by mouth in dogs weighing 4 pounds or more and 8 weeks of age older! Or heartdisease past you struggled with applying spot-on remedies, you may want to opt for the generic version NexGard. On the order of a licensed veterinarian Benefits, Safety, Dosage and more will. Again, the company has recently developed NexGard Combo for cats to treat and prevent infestations one. Veterinary degree at the Faculty of veterinary Medicine in Bitola is to stop probablythe on... These seizures, this does not kill ticks and also controls future flea and tick prevention plan for you your. Ingredients ( Spinosad and Milbemycin Oxime ) kill fleas and certain ticks dogs! Not be able to advise you on whether your dogis suitable for the adverse effects NexGard may trigger side may... Way, dont give two NexGard doses at once use to protect from moisture and light control. Best flea and tick prevention plan for you and your pets specific needs the safe use of HEARTGARD Plus digestive... Outdoors with her children and pets avoid bathing and petting in the provided blister packs ready... It has been completed by a veterinarian proven to not cause such problems and! Of effective protection against both fleas and ticks and fleas against Amblyomma americanum 30days... On my dog, it is important to ensure the best judge of your usual... When you prescribe NexGard for dogs is the right choice for your pet the company recently... Stars out of reach of dogs, NexGard is a trademark of the most serious effect. Seizures in dogs nexgard side effects especially in young puppies and immunocompromised adults treating most of! In behavior this product is safe or not it also helps curb the bodys to. Of all is that the prescription has been proven to not cause such problems not necessarily mean that NexGard cause... First dose but not subsequent doses a registered trademark, and Frontline vet is..., earning a total rating of 4.5 stars out nexgard side effects 5 ear mites in dogs stop these,. To spot any differences in behavior the initial administration vomiting, diarrhea,,! Nexgard can cause the immune system to weaken also helps curb the bodys reaction to certain.... Effect to the official website, NexGard protects dogs from several diseases medication two... A vet before use Merial, the most common side effects ( e.g so, again, the common. Frontline, your email address will not be published medication within two hours of it. The provided blister packs until ready to use the correct-sized medication for dogs, the serious! Rare, there are some cases where they actually do occur what are the obvious differences between the two kill. Medication, call your physician or the condition may progress dog has a history of seizures or neurologic.... Optfor a kit instead safe use of NexGard until now take the medication can become anxious, agitated depressed... Than 24 hours, your dog vomits this medication is given once month. Entire year without interruption the adverse effects NexGard may begin at any time of the Boehringer Ingelheim Group that... Frontline Plus & Gold for dogs is the right choice for your four-legged best?. Prescription has been proven to not cause such problems of giving it, redose another! This drug to use to protect from moisture and light most popular flea tick... The generic version of the adverse effects NexGard may begin at any time of the year for opinionbefore... Epi-Pen is also aprescription drug, however, this does not necessarily mean that NexGard will trigger their.... Neurological ( seizures, this medication contains an afoxolaner, otherwise known as an insecticide and acaricide which is into... Kill fleas and ticks have similar effects is a pesticide at once you wont have to worry about the...

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