Adverse effects of antidepressants reported by a large international cohort: emotional blunting, suicidality, and withdrawal effects, Being less able to laugh or cry even when appropriate, Not being able to respond with the same level of enjoyment that you normally would. Related: Prozac side effects (in more detail). Nierenberg AA, Farabaugh AH, Alpert JE, et al. Pharmacotherapy for generalized anxiety disorder in adult and pediatric patients: An evidence-based treatment review. Given that not everyone on antidepressants will develop emotional blunting, it has been difficult for scientists to tease out a precise reason for this effect. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Prozac only for the indication prescribed. Prozac can be an activating antidepressant and can lead to side effects in the first few weeks that may impact your response, such as insomnia (trouble sleeping), anxiety or nervousness. Get regular exercise, such as jogging, biking or aerobics, or some type of physical activity, such as walking. Treatment effectiveness and tolerability outcomes that are most important to individuals with bipolar and unipolar depression. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. If you think youve taken too much Prozac, call 911 or local emergency services or go to an emergency room to get help right away. If you have trouble sleeping, try some relaxation techniques before bedtime, such as reading, taking a bath, And limit your intake of sugary and processed, Sexual side effects, such as decreased libido, erectile dysfunction, and delayed ejaculation, While it has proven to help alleviate the debilitating symptoms of certain mental disorders that affect cognitive functioning, Prozac comes with, linked to an increased risk of heart problems. Common medications that may interact with Prozac include: Avoid drinking alcohol or taking illegal or recreational drugs while taking Prozac. Dry mouth is a common side effect of many antidepressants. Prozac can cause mania, which is characterized by symptoms such as abnormal elation, decreased need for sleep, grandiose thoughts, racing thoughts, impulsive behavior, and reckless decision-making. Bielski RJ, et al. Within the first one to two weeks, most people feel lower levels of anxiety, restlessness or tiredness with Prozac treatment. I'm on 60mg of prozac for MDD and GAD, it's given me the opportunity to work on myself (physically and mentally). Some locations already provide limited genetic testing to help determine antidepressant choice, but testing is not routine and it's not always covered by insurance. Revision date: February 28, 2023. sertraline, trazodone, alprazolam, fluoxetine, clonazepam, Lexapro, amitriptyline, quetiapine, venlafaxine, Zoloft. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b050b0ee-107c-4f82-8031-92ec68baa6a2#section-5.10. Certain antidepressants should not be used if you already have heart problems or if you're taking an MAOI. This is more likely to occur when Prozac is first started, or the dose is increased. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. In lower weight children, initiate treatment with a dose of 10 mg/day. You may gain weight because of fluid retention or lack of physical activity, or because you have a better appetite when your depression symptoms ease up. And if you want to learn more about brain fog and how to clear it effectively, here are some educational blog posts to read, and feel free to join this online community of brain health enthusiasts. Be sure to tell a doctor or pharmacist about all of the medications and OTC products you take. Fluoxetine prescribing information. Another serious syndrome, called Neuroleptic Malignant Syndrome, has also been reported; symptoms include high body temperature, muscle rigidity, and mental disturbances. Ask your doctor for advice on stool softeners if other measures don't work. Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. Some experts have even questioned whether blunting is a side effect of antidepressant treatment or perhaps a partial failure of the drug itself.. Anxiety, low sodium levels, and allergic reactions (including rash) can also occur. Breathe through your nose, not your mouth. Some common side effects in people taking Prozac for obsessive-compulsive disorder (OCD) include: insomnia nausea diarrhea decreased appetite and weight loss* sleepiness Some common side effects. Weight gain is not a common side effect with Prozac treatment, and some patients may lose weight, although this can be temporary. Symptoms of brain fog due to Prozac intake can vary from person to person, but here are the most common ones: If you feel any of these symptoms, especially when it gets severe, we highly recommend that you consult your doctor and have them evaluate your Prozac dosage. It also releases endorphins, which can help boost your mood. Also report any eye pain, eye swelling, or visual disturbances; seizures; manic behavior such as recklessness, racing thoughts, increased energy, or severe difficulty sleeping. 2018;13(3):176-186. doi:10.2174/1574886313666180605095130. Sexual side effects can be ongoing if not addressed by your healthcare provider. health information, we will treat all of that information as protected health It is more likely to cause insomnia than drowsiness. Common side effects include: Anxiety Blurred vision Diarrhea Dizziness Dry mouth Fatigue Headaches Heartburn Loss of appetite Lightheadedness Nausea Sleep problems Sexual problems Sweating Yes, Prozac can cause brain fog. Prozac is a common antidepressant prescribed to treat depression that cannot be mixed with other medications or illicit drugs. Peak plasma concentrations occur within six to eight hours of a single dose. Avoid Prozac if youre allergic to any of its ingredients. A doctor will decide the best dosage of Prozac for you based on your condition and how you respond to treatment. FDA. Prozac may be used for the treatment of depression and other mood disorders. A healthy diet can help improve your cognitive function, especially focus and concentration. Accessed Aug. 26, 2019. Drug class: selective serotonin reuptake inhibitors, https://www.drugs.com/pro/prozac-weekly.html, Prozac is a brand (trade) name for fluoxetine which may be used to treat some mood or eating disorders. J Affect Disord. Migraines: Are they triggered by weather changes? 3. Signs and symptoms such as nausea, weight gain or sleep problems can be common initially. Dont suddenly stop taking Prozac without talking with a doctor. According to the research, the antidepressants most commonly associated with emotional blunting fall into one of three classes: Though the percentage of people who experienced emotional blunting was similar between the three drug classes, there were variations. nimh.nih.gov/health/publications/anxiety-disorders/treatment-of-anxiety-disorders.shtml, adaa.org/understanding-anxiety/facts-statistics, dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c88f33ed-6dfb-4c5e-bc01-d8e36dd97299, ncbi.nlm.nih.gov/pmc/articles/PMC6340395/, ncbi.nlm.nih.gov/pmc/articles/PMC4090227/, psychiatry.org/patients-families/anxiety-disorders/what-are-anxiety-disorders, My Anxiety Makes My Brain Feel Like a Broken Hamster Wheel, 13 Daily Hacks for Someone with Social Anxiety, Catastrophizing: What You Need to Know to Stop Worrying, Anxiety and Loss of Appetite: What to Do About It, Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, Social Anxiety: Odors from Other Peoples Sweat May Help Ease Symptoms, 7 of the Best Weighted Blankets for Anxiety, Breaking the Cycle of Anxiety and Avoidance, oral medication with convenient, once-daily dosing, generic available, making it more affordable, not approved for generalized anxiety disorder, may cause anxiety, trouble sleeping, and nervousness. All selective serotonin reuptake inhibitors are associated with various side effects, many of which are similar. Unipolar major depression in adults: Choosing initial treatment. Prozac has been linked to reports of visual problems, such as blurred vision and tunnel vision. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Drink plenty of fluids, such as cool water. A smaller study from New Zealand involving 180 people on long-term antidepressant therapy found that 64.5% experienced emotional blunting. Eat high-fiber foods, such as fresh fruits and vegetables, brans, and whole grains. Accessed Aug. 27, 2019. Hypothyroidism: Can calcium supplements interfere with treatment? 2017. Shared decision making for antidepressants in primary care: A cluster randomized trial. Selective serotonin reuptake inhibitors (SSRIs) are more likely to cause sexual side effects than other antidepressants are. We avoid using tertiary references. Emotional blunting means that your feelings and emotions are so dulled that you neither feel up nor down. Though your depression symptoms may have improved, the overwhelming waves of gloom can sometimes be replaced by an emotional inertness in which are neither able to cry nor share a real belly laugh. Serotonin: What It Is, How to Increase It, and Can You Have Too Much? Curr Drug Saf. These side effects may be temporary, lasting a few days to weeks. Prozac is best tapered down slowly on discontinuation. Advertising revenue supports our not-for-profit mission. Prozac belongs to a group of medicines called Selective Serotonin Re-uptake Inhibitors (SSRIs). (2020). While the exact way SSRIs work isnt known, one of the ways its thought to work is by regulating your mood by increasing the levels of serotonin in your brain. Practice deep-breathing exercises, muscle relaxation or yoga. Prozac vs Zoloft - What are the Differences & Similarities? This discord family is a safe place where we can all (anonymously if we choose) talk about and seek help for what is going on in our heads. Accessed Aug. 26, 2019. "Emotional numbness" was ranked number one, with 70.6% experiencing the symptom. Others still have suggested that emotional blunting is more of a symptom revealed, meaning that once the antidepressants are able to alleviate depression, the underlying symptoms of emotional blunting are revealed rather than caused. In general, theres not a significant difference between using one or the other for the purposes of anxiety treatment. Continue working with your doctor to find the right formula of medications, therapy, and lifestyle to overcome and manage your depression over the long term. Be alert for racing or impulsive thoughts along with high energy. You simply feel "blah." Francois D, et al. Some studies indicate that variations in genes may play a role in the effectiveness and risk of side effects of specific antidepressants. You simply feel "blah." Do you feel like your brain is in a fog when you take Prozac? Depression in women: Understanding the gender gap, Depression: Provide support, encouragement, Depression: Supporting a family member or friend, Diabetes and depression: Coping with the two conditions. To get you started, weve rounded up the best weighted. Antidepressant drugs are often an effective way to treat depression and anxiety in children and teenagers. https://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-revised-recommendations-celexa-citalopram-hydrobromide-related#professionals. If these develop, talk to your doctor right away because they may be signs of bipolar disorder or another serious disorder. Free shipping for many products! Experts believe fluoxetine's effects are due to its ability to block the reuptake of serotonin by nerves, leading to an increase in serotonin concentrations in the nerve synapse (space between two nerves). Some of these Prozac side effects include brain fog, serotonin syndrome, bleeding problems, heart problems, low sodium levels in the blood, mania, seizures, and visual problems. Some antidepressants may cause insomnia, making it difficult to get to sleep or stay asleep, so you may be tired during the day. Anxiety and Depression Are Better Correlates of Parkinson's Disease Quality of Life Than Apathy. Prozac can cause a number of other side effects, in addition to brain fog. include protected health information. For many people, these improve within weeks of starting an antidepressant. Share your medical and family history with a doctor and ask about the risks of Prozac. information submitted for this request. If you experience any unusual chest pain, shortness of breath, or swelling in your legs or ankles while taking Prozac, consult your doctor immediately. For best absorption, dont take it alongside a fiber or vitamin supplement. I got Zoloft from my doctor. What are the signs and symptoms of hidradenitis suppurativa? Introduction. Daily Tips for a Healthy Mind to Your Inbox, Small Ways to Feel Better When You're Depressed, Selective norepinephrine reuptake inhibitors, Tricyclic and tetracyclic antidepressants. Symptoms of Emotional Blunting Emotional blunting means that your feelings and emotions are so dulled that you neither feel up nor down. While it would seem fair to assume that serotonin plays a role in the effect (given the lower incidence among Wellbutrin users), most scientists believe that a single hormone cannot be to blame. This video has been medically reviewed by John C. Umhau, MD, MPH, CPE. 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